Trost, Barry M.; Schaeffner, Benjamin; Osipov, Maksim; Wilton, Donna A. A. published the artcile< Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation of β-ketoesters: An Unusual Counterion Effect>, COA of Formula: C54H42N2O2P2, the main research area is stereoselective decarboxylative allylic alkylation keto ester palladium catalyst.
The palladium-catalyzed decarboxylative asym. allylic alkylation of β-keto esters is reported. This reaction was applied to the synthesis of (-)-ranirestat. It was expanded to β-keto esters by using allyl chloroformate to form allyl enol carbonates in situ. Two sets of reaction conditions were developed to fine-tune the enantioselectivity.
Angewandte Chemie, International Edition published new progress about Allylic alkylation (decarboxylative, stereoselective). 152140-65-3 belongs to class chiral-phosphine-ligands, and the molecular formula is C54H42N2O2P2, COA of Formula: C54H42N2O2P2.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate