《Water-Promoted Palladium-Catalyzed Asymmetric Ring-Opening of Oxabenzonorbornadienes with Alkoxysilanes》 was published in Advanced Synthesis & Catalysis in 2020. These research results belong to Tan, Yun; Yao, Yongqi; Yang, Wen; Lin, Qifu; Huang, Guobao; Tan, Minxiong; Chen, Shuqi; Chen, Donghan; Yang, Dingqiao. Application In Synthesis of (S)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole The article mentions the following:
Water-promoted palladium-catalyzed asym. ring-opening (ARO) reaction of oxabenzonorbornadienes with a wide variety of alkoxysilanes was developed in a one-pot fashion, yielding cis-1,2-dihydronaphthalen-1-ols I [R1 = CH=CH2, Ph, 1-naphthyl, etc.; R2 = H, OMe; R3 = H, Me, Br, etc.; R4 = H, Me, F, etc.; R5 = H, OMe] in favorable yields (up to 98%) with gratifying enantioselectivities (up to 98% ee) under mild conditions. Furthermore, the cis-1,2-configuration of product was established by X-ray diffraction anal., and a possible mechanism for the present catalytic ring-opening reaction was also proposed. In the experiment, the researchers used many compounds, for example, (S)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole(cas: 210169-54-3Application In Synthesis of (S)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole)
(S)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole(cas: 210169-54-3) is a chelating ligand used to prepare coordination complex catalysts, such as its use in Pd catalysts for the enantioselective synthesis of spiro- or benzofused hetereocycles with exocyclic olefins via enantioselective intramolecular dearomative Heck reaction of indoles, benzofurans, pyrroles and furans.Application In Synthesis of (S)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis