Qiu, Min; Hu, Xiang-Ping; Wang, Dao-Yong; Deng, Jun; Huang, Jia-Di; Yu, Sai-Bo; Duan, Zheng-Chao; Zheng, Zhuo published an article in Advanced Synthesis & Catalysis. The title of the article was 《Chiral 1,2,3,4-tetrahydro-1-naphthylamine-derived phosphine-phosphoramidite ligand (THNAPhos): application in highly enantioselective hydrogenations of functionalized C=C bonds》.Recommanded Product: 960128-64-7 The author mentioned the following in the article:
The authors recently reported a new chiral 1,2,3,4-tetrahydro-1-naphthylamine-derived phosphine-phosphoramidite ligand, (Rc,Ra)-THNAPhos, which is highly efficient in the Rh-catalyzed asym. hydrogenation of a broad range of α-enol ester phosphonates. To further demonstrate the utility of THNAPhos in asym. hydrogenation, its new application in the asym. hydrogenation of α-dehydroamino esters, enamides, itaconate, and α-enamido phosphonates was described. The Rh/(Rc,Ra)-THNAPhos complex is highly effective for the enantioselective hydrogenation of these kinds of olefins, affording the products in excellent enantioselectivity (normally >99% ee).(R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydronaphthalen-1-amine(cas: 960128-64-7Recommanded Product: 960128-64-7) was used in this study.
(R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydronaphthalen-1-amine(cas:960128-64-7) is one of aminophosphine type ligands. An increased interest in aminophosphine type ligands used for asymmetric synthesis has been witnessed.Recommanded Product: 960128-64-7 This growth in popularity of aminophosphine ligands in asymmetric synthesis is in part due to the growing number of convenient synthetic pathways leading to useful ligand sets.
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis