In 2017,Chemistry – A European Journal included an article by Zhang, Wanli; Ma, Shengming. Recommanded Product: 256390-47-3. The article was titled 《Palladium-Catalyzed Enantioselective Alkoxycarbonylation of Propargylic Carbonates with (R)- or (S)-3,4,5-(MeO)3-MeOBIPHEP》. The information in the text is summarized as follows:
(R)- and (S)-3,4,5-(MeO)3-MeOBIPHEP were identified as the efficient chiral ligands for the Pd-catalyzed highly enantioselective synthesis of 2,3-allenoates from different types of easily available racemic propargylic carbonates with 90-98% ee and decent yields. The potential of the products was demonstrated with high chirality transfer efficiency. In addition to this study using (R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,4,5-trimethoxyphenyl)phosphine], there are many other studies that have used (R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,4,5-trimethoxyphenyl)phosphine](cas: 256390-47-3Recommanded Product: 256390-47-3) was used in this study.
(R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,4,5-trimethoxyphenyl)phosphine](cas: 256390-47-3) belongs to chiral phosphine ligands. Nucleophilic phosphine catalysis often involves the formation of Lewis adducts, namely phosphonium (di)enolate zwitterions, as reaction intermediates. These intermediates are formed through nucleophilic attack of the phosphine catalysts at electron-poor nuclei (normally carbon atoms) and then proceed through several steps to form new chemical bonds. Recommanded Product: 256390-47-3
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis