In 2019,Organic & Biomolecular Chemistry included an article by Wang, Kaiye; Xiang, Yanan; Shi, Zhujun; Wang, Hongyu; Li, Na; Tang, Bo. Reference of (S)-1-(Diphenylphosphino)-3,3-dimethylbutan-2-amine. The article was titled 《Asymmetric kinetic resolution of sulfides for the construction of unsymmetric sulfides and chiral 3,3-disubstituted oxindoles》. The information in the text is summarized as follows:
An enantioselective method was developed for the synthesis of unsym. disulfides R’SSR” [R’ = allyl, CH2CO2Me, Bn, etc.; R” = 4-FC6H4, 4-BrC6H4, Bn] and chiral 3,3-disubstituted oxindoles I [R1 = allyl, 4-BrC6H4, Bn, etc.; X = H, 5-Br, 5-I, 6-Br; R2 = Me, PMB] in one step from oxindoles and thiols using chiral phosphines catalyst. Many substituted thiols and 3,3-disubstituted oxindoles were well tolerated and produced high yields and enantioselectivities under mild conditions. In the experimental materials used by the author, we found (S)-1-(Diphenylphosphino)-3,3-dimethylbutan-2-amine(cas: 286454-86-2Reference of (S)-1-(Diphenylphosphino)-3,3-dimethylbutan-2-amine)
(S)-1-(Diphenylphosphino)-3,3-dimethylbutan-2-amine(cas:286454-86-2) is one of aminophosphine type ligands. An increased interest in aminophosphine type ligands used for asymmetric synthesis has been witnessed.Reference of (S)-1-(Diphenylphosphino)-3,3-dimethylbutan-2-amine This growth in popularity of aminophosphine ligands in asymmetric synthesis is in part due to the growing number of convenient synthetic pathways leading to useful ligand sets.
Referemce:
Phosphine ligand,
Chiral phosphines in nucleophilic organocatalysis