Valli, Matteo; Bruno, Paolo; Sbarbada, Davide; Porta, Alessio; Vidari, Giovanni; Zanoni, Giuseppe published the artcile< Stereodivergent Strategy for Neurofuran Synthesis via Palladium-Catalyzed Asymmetric Allylic Cyclization: Total Synthesis of 7-epi-ST-Δ8-10-Neurofuran>, Computed Properties of 152140-65-3, the main research area is neurofuran synthesis asym allylic cyclization.
An enantioselective stereodivergent approach to two key neurofuran precursors, belonging to the AC and ST classes, has been developed starting from a single achiral precursor. The absolute configuration of the THF cores was secured by a Pd-catalyzed asym. allylic alkylation. From the ST precursor, 7-epi-ST-Δ8-10-neurofuran (I) was prepared
Journal of Organic Chemistry published new progress about Allylic alkylation, stereoselective. 152140-65-3 belongs to class chiral-phosphine-ligands, and the molecular formula is C54H42N2O2P2, Computed Properties of 152140-65-3.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate