Najera, Carmen; de Gracia Retamosa, M.; Sansano, Jose M.; de Cozar, Abel; Cossio, Fernando P. published the artcile< Enantioselective synthesis of polysubstituted prolines by Binap-silver-catalyzed 1,3-dipolar cycloadditions>, Related Products of 139139-93-8, the main research area is polysubstituted proline derivative asym preparation; iminoester maleimide asym dipolar cycloaddition silver BINAP; silver BINAP asym dipolar cycloaddition catalyst.
The enantioselective 1,3-dipolar cycloaddition reaction of stabilized azomethine ylides, generated from iminoesters, with maleimides was efficiently achieved by intermediacy of an equimolar mixture of chiral (R)- or (S)-Binap and AgClO4. The high stability of the titled catalytic metal-complex to light exposure and its insolubility in toluene made possible its recovery and reutilization in other new process. In order to get a better understanding of the behavior of these chiral catalysts, we have carried out DFT1 calculations demonstrating the exptl. observed high enantio- and endo-selectivity through a very asynchronous transition state.
Tetrahedron: Asymmetry published new progress about 1,3-Dipolar cycloaddition reaction, stereoselective. 139139-93-8 belongs to class chiral-phosphine-ligands, and the molecular formula is C44H40P2, Related Products of 139139-93-8.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate