Michon, Christophe; Bethegnies, Aurelien; Capet, Frederic; Roussel, Pascal; de Filippis, Arnault; Gomez-Pardo, Domingo; Cossy, Janine; Agbossou-Niedercorn, Francine published the artcile< Catalytic Asymmetric Allylic Alkylation of 3-Arylated Piperidin-2-ones>, HPLC of Formula: 152140-65-3, the main research area is preparation chiral allyl pyrimidine derivative asym alkylation catalysis.
The preparation of optically active lactams from 3-aryl-2-piperidinone is reported. The quaternary carbon stereo-centers were formed using palladium-catalyzed asym. allylic alkylation reactions. The resulting enantio-enriched compounds are useful intermediates for the synthesis and development of neurokinin antagonists.
European Journal of Organic Chemistry published new progress about Alkylation, stereoselective (allylic). 152140-65-3 belongs to class chiral-phosphine-ligands, and the molecular formula is C54H42N2O2P2, HPLC of Formula: 152140-65-3.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate