Kishore, Nand; Holden, Marcia J.; Tewari, Yadu B.; Goldberg, Robert N. published the artcile< A thermodynamic investigation of some reactions involving prephenic acid>, Application of C21H27N7Na2O14P2, the main research area is thermodn prephenate dehydratase dehydrogenase.
Calorimetric enthalpies of reaction have been measured for the following enzyme-catalyzed reactions at the temperature 298.15 K: prephenate(aq) = phenylpyruvate(aq) + carbon dioxide(aq), prephenate(aq) + NADox(aq) + H2O(l) = 4-hydroxyphenylpyruvate(aq) + NADred(aq) + carbon dioxide(aq). Here, NADox and NADred are, resp., the oxidized and reduced forms of β-NAD. The enzymes that catalyze these resp. reactions, prephenate dehydratase and prephenate dehydrogenase, were prepared by expression of the appropriate plasmids using the techniques of mol. biol. The calorimetric measurements together with the equilibrium modeling calculations lead to a standard molar enthalpy change ΔrHom = -(126±5) kJ·mol-1 for the reference reaction: prephenate2-(aq) = phenylpyruvate-(aq) + HCO3-(aq). Similarly, ΔrHom = -(74±3) kJ·mol-1 for the reference reaction: prephenate2-(aq) + NADox-(aq) + H2O(l) = 4-hydroxyphenylpyruvate-(aq) + NADred2-(aq) + HCO3-(aq) + H+(aq). Both results pertain to T = 298.15 K and ionic strength I = 0. Benson estimates for the entropies lead to approx. values of the equilibrium constants K ≈ 1×1026 and K ≈ 1×1012, resp., for the above two reference reactions. (c) 1999 Academic Press.
Journal of Chemical Thermodynamics published new progress about Equilibrium constant. 606-68-8 belongs to class chiral-phosphine-ligands, and the molecular formula is C21H27N7Na2O14P2, Application of C21H27N7Na2O14P2.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate