Hatano, Manabu; Terada, Masahiro; Mikami, Koichi published the artcile< Highly enantioselective palladium-catalyzed ene-type cyclization of a 1,6-enyne>, Quality Control of 139139-93-8, the main research area is furan vinyl methoxycarbonylmethylidene methyl preparation enantioselective; palladium catalyzed carbocyclization enyne; crystal structure vinylmethylcaboxymethylidenefuran phenylethylamine salt; asymmetric catalysis; cyclizations; enynes; palladium.
The authors developed a highly efficient palladium(II)-catalyzed ene-type carbocyclization of 1,6-enyne MeCH=C(Me)CH2OCH2CCCO2Me leading to enantiopure furan (I). This highly enantioselective catalysis is applicable for the construction of an enantioenriched quaternary chiral center. Possible mechanisms including neutral and cationic intermediate have been proposed.
Angewandte Chemie, International Edition published new progress about Alkenynes Role: RCT (Reactant), RACT (Reactant or Reagent). 139139-93-8 belongs to class chiral-phosphine-ligands, and the molecular formula is C44H40P2, Quality Control of 139139-93-8.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate