Chang, Xin; Ma, Pei-Long; Chen, Hong-Chao; Li, Chuan-Ying; Wang, Peng published the artcile< Asymmetric Synthesis and Application of Chiral Spirosilabiindanes>, Quality Control of 139139-93-8, the main research area is alkenyldihydrosilane preparation rhodium catalyzed asym double hydrosilation spirocyclization; spirosilabiindane chiral preparation reaction aminophosphine; phosphoramidite spirosilabiindane chiral preparation catalyst ligand asym hydrogenation carboamination; crystal structure chiral spirosilabiindane diol derivative phosphoramidite; mol structure chiral spirosilabiindane diol derivative phosphoramidite; asymmetric catalysis; ligand design; silanes; spirocompounds; synthetic methods.
Reported here is the development of a class of chiral spirosilabiindane scaffolds by Rh-catalyzed asym. double hydrosilation, for the 1st time. Enantiopure SPSiOL (spirosilabiindane diol), a new type of chiral building block for the preparation of various chiral ligands and catalysts, was readily prepared on >10 g scale using this protocol. The potential of this new spirosilabiindane scaffold in asym. catalysis was preliminarily demonstrated by development of the corresponding monodentate phosphoramidite ligands (SPSiPhos), which were used in both a Rh-catalyzed hydrogenation and a Pd-catalyzed intramol. carboamination.
Angewandte Chemie, International Edition published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (bis(alkenyl)dihydrosilanes). 139139-93-8 belongs to class chiral-phosphine-ligands, and the molecular formula is C44H40P2, Quality Control of 139139-93-8.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate