Kaiser, Thomas M.; Yang, Jiong published the artcile< Catalytic Enantioconvergent Decarboxylative Allylic Alkylation of Allyl Indolenine-3-carboxylates>, SDS of cas: 152140-65-3, the main research area is indole allyl asym synthesis; indolenine carboxylate allyl preparation enantioconvergent decarboxylative allylic alkylation.
A catalytic enantioconvergent process has been developed for the conversion of racemic allyl indolenine-3-carboxylates I (R1 = H, Cl, Me, MeO; R2 = MeCOCH2CH2, MeCH:CHCH2, PhCH2, 2-naphthylmethyl, etc.; R3 = H2C:CH, MeCH:CH, H2C:CMe) into enantiomerically enriched C3-quaternary indolenines II. A Pd-catalyzed decarboxylative allylic alkylation reaction was employed for both stereoablation of the racemic allyl indolenine-3-carboxylates and enantioselective formation of the quaternary carbon center.
European Journal of Organic Chemistry published new progress about Allylic alkylation catalysts, stereoselective. 152140-65-3 belongs to class chiral-phosphine-ligands, and the molecular formula is C54H42N2O2P2, SDS of cas: 152140-65-3.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate