Franckevicius, Vilius; Cuthbertson, James D.; Pickworth, Mark; Pugh, David S.; Taylor, Richard J. K. published the artcile< Asymmetric Decarboxylative Allylation of Oxindoles>, Computed Properties of 152140-65-3, the main research area is stereoselective palladium catalyzed decarboxylative allylation oxindole allyl ester; oxindole allyl derivative stereoselective preparation; stereoselectivity reversal substituent size facial selectivity allylation.
An asym. decarboxylative palladium-catalyzed allylation of alkyl- and aryl-substituted oxindoles has been developed, enabling the installation of an all-carbon quaternary chiral center at the oxindole 3-position in excellent yields and good to excellent enantioselectivity. An intriguing substrate-dependent reversal in stereoselectivity has been observed, whereby the size of the substituent determines the facial selectivity in the allylation step.
Organic Letters published new progress about Allylation catalysts, stereoselective (decarboxylative). 152140-65-3 belongs to class chiral-phosphine-ligands, and the molecular formula is C54H42N2O2P2, Computed Properties of 152140-65-3.
Referemce:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate