The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1-(Bromomethyl)-2-iodobenzene, is researched, Molecular C7H6BrI, CAS is 40400-13-3, about Visible light mediated synthesis of 6H-benzo[c]chromenes: transition-metal-free intramolecular direct C-H arylation, the main research direction is halophenylbenzyl ether halobenzyl phenyl intramol direct arylation; benzochromene preparation green chem visible light.Synthetic Route of C7H6BrI.
A synthetic approach towards the 6H-benzo[c]chromene ring under visible light and transition-metal-free conditions has been developed. Benzochromenes are synthesized from the corresponding (2-halobenzyl) Ph ethers or (2-halophenyl) benzyl ethers using KOtBu in DMSO (DMSO) at room temperature (rt) and blue light-emitting diodes (LEDs) as the light source. This methodol. replaces the use of ligands or additives, high temperatures and toxic solvents. The photostimulated reaction exhibits very good tolerance to different functional groups and 5H-dibenzo[c,f]chromenes are also effectively obtained. An electron donor-acceptor complex formed by the dimsyl anion and (2-halobenzyl) Ph ethers was found and it induces the ET as the initial step in the photocyclization reaction. Furthermore, in order to explain the regiochem. outcome of this reaction, a theor. anal. was performed using DFT methods.
This compound(1-(Bromomethyl)-2-iodobenzene)Synthetic Route of C7H6BrI was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate