In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called CuSO4-Catalyzed dual annulation to synthesize O, S or N-containing tetracyclic heteroacenes, published in 2020, which mentions a compound: 40400-13-3, mainly applied to benzofuroindole benzothienoindole indoloindole preparation; halobenzyl halide nitrile tandem dual annulation copper redox catalyst, Quality Control of 1-(Bromomethyl)-2-iodobenzene.
In this work, CuSO4 was utilized as a practical redox catalyst for tandem dual annulation in the synthesis of indole-fused tetracyclic heteroacenes such as benzofuro- I [R1 = H, 2-Me, 2-Br, etc.; R2 = H, 8-MeO, 7-Br, etc.; X = O], benzothieno- I [R1 = H, 3-MeO, 4-Br, etc.; R2 = H; X = S] and indoloindoles I [R1 = H, 3-Cl, 4-Br, etc.; R2 = H, 2-Br; X = NMe, nBuN, NPh, etc.] which were important skeletons in both medicinal chem. and materials chem. The preparation of such skeletons in a convenient and efficient manner was in high demand. This method realized the modular synthesis of benzofuro-, benzothieno- and indoloindoles from abundant feedstocks such as 2-halobenzyl halides and nitrile derivatives in up to 99% yields, providing a rapid access to diverse indole-fused heteroacenes with biol. or optoelectronic properties.
The article 《CuSO4-Catalyzed dual annulation to synthesize O, S or N-containing tetracyclic heteroacenes》 also mentions many details about this compound(40400-13-3)Quality Control of 1-(Bromomethyl)-2-iodobenzene, you can pay attention to it or contacet with the author([email protected]; [email protected]; [email protected]) to get more information.
Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate