The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1-(Bromomethyl)-2-iodobenzene, is researched, Molecular C7H6BrI, CAS is 40400-13-3, about 1-Alkyl-3-alkylindolin-2-imine hydrochlorides as useful building blocks in the copper-catalyzed synthesis of polycyclic indoline scaffolds, the main research direction is dihydro indoloquinoline preparation; tetrahydro indoloquinoline preparation.Reference of 1-(Bromomethyl)-2-iodobenzene.
A novel and efficient copper-catalyzed synthesis of dihydro-6H-indolo[2,3-b]quinoline derivatives I [R1 = H, 9-Me, 9-F, etc.; R2 = Me, Et, Bn, etc.; R3 = Me, Ph, Bn,etc.; R4 = H, 2-OMe, 2-Cl, etc.] was synthesized using 3-alkyl-1-alkylindolin-2-imine hydrochlorides as the building blocks. Furthermore, easy reduction of compounds I with diisobutylaluminum hydride provided tetrahydro-6H-indolo[2,3-b]quinoline derivatives II [R5 = H, 7,9-(Me)2; R6 = Me, Bn; R7 = Et, n-Pr, Bn, 4-MeOC6H4CH2] in excellent yields. The present method showed some advantages including use of cheap cuprous chloride as the catalyst and tolerance of wide functional groups.
Although many compounds look similar to this compound(40400-13-3)Reference of 1-(Bromomethyl)-2-iodobenzene, numerous studies have shown that this compound(SMILES:BrCC1=C(I)C=CC=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate