Related Products of 1824-94-8. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: (2R,3R,4S,5R,6R)-2-(Hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol, is researched, Molecular C7H14O6, CAS is 1824-94-8, about Synthesis of Hexane-Tetrols and -Triols with Fixed Hydroxyl Group Positions and Stereochemistry from Methyl Glycosides over Supported Metal Catalysts. Author is Krishna, Siddarth H.; Cao, Ji; Tamura, Masazumi; Nakagawa, Yoshinao; De Bruyn, Mario; Jacobson, Graeme S.; Weckhuysen, Bert M.; Dumesic, James A.; Tomishige, Keiichi; Huber, George W..
Carbohydrates are a renewable feedstock for the production of partially reduced polyols, but typical hydrogenolysis processes are unselective towards C-O bond cleavage at different positions and erase the stereocenters present in the feedstock. In this study, we demonstrate the synthesis of new types of acyclic polyols with controlled stereochem. from Me glycosides. Products include (2R,3S)-1,2,3,6-hexanetetrol, (2R,5S)-1,2,5,6-hexanetetrol, (2S,5S)-1,2,5-hexanetriol, and (4R,5S)-1,4,5-hexanetriol. Me glycosides are first selectively dehydrated and hydrogenated to Me dideoxy-glycosides as reported in previous work. These Me dideoxy-glycosides are then converted to hexane- triols and -tetrols over Pt-based catalysts in water in 80-95% yield via methoxy bond hydrolysis and hydrogenation. This route largely preserves the stereocenters of the remaining hydroxyl groups (>92% stereo-purity). The nature of the intermediates formed depends on the structure of the glycoside feedstock. 3,4-Dideoxy-glycosides can undergo loss of the C2-OH stereo-center due to an aldose-ketose isomerization reaction, which can be mitigated by using a bifunctional metal-acid catalyst to facilitate the reaction at lower temperature By demonstrating a new route to produce renewable polyols with controlled hydroxyl group positions and stereochem., this report lays the groundwork for further research into the applications of these mols. in the chem. industry.
In addition to the literature in the link below, there is a lot of literature about this compound((2R,3R,4S,5R,6R)-2-(Hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol)Related Products of 1824-94-8, illustrating the importance and wide applicability of this compound(1824-94-8).
Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate