Computed Properties of C7H6BrI. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 1-(Bromomethyl)-2-iodobenzene, is researched, Molecular C7H6BrI, CAS is 40400-13-3, about Enantioselective synthesis of isochromans and tetrahydroisoquinolines by C-H insertion of donor/donor carbenes. Author is Nickerson, Leslie A.; Bergstrom, Benjamin D.; Gao, Mingchun; Shiue, Yuan-Shin; Laconsay, Croix J.; Culberson, Matthew R.; Knauss, Walker A.; Fettinger, James C.; Tantillo, Dean J.; Shaw, Jared T..
Using donor/donor carbenes and Rh2(R-PTAD)4 as a catalyst, a collection of isochroman substrates I (R1 = Me, 4-NCC6H4, 4-MeOC6H4, 3-pyridyl, R2 = 4-MeOC6H4; R1 = Ph, R2 = MeCC, H2C:CMe, PhCH:CH, Ph, etc.) was synthesized in good yields with excellent diastereo- and enantioselectivity from the corresponding hydrazones II, and no rearrangement products were observed Furthermore, this procedure was applied to the first synthesis of tetrahydroisoquinolines via C-H insertion. In one case, a Stevens rearrangement product was isolated at elevated temperature from a carbamate-protected amine substrate, and computational evidence suggested formation through a free ylide not bound to rhodium.
In addition to the literature in the link below, there is a lot of literature about this compound(1-(Bromomethyl)-2-iodobenzene)Computed Properties of C7H6BrI, illustrating the importance and wide applicability of this compound(40400-13-3).
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Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate