Computed Properties of C7H6BrI. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1-(Bromomethyl)-2-iodobenzene, is researched, Molecular C7H6BrI, CAS is 40400-13-3, about Pd(II)-Catalyzed Synthesis of Benzocyclobutenes by β-Methylene-Selective C(sp3)-H Arylation with a Transient Directing Group.
Methylene-selective C-H functionalization is a significant hurdle that remains to be addressed in the field of Pd(II) catalysis. A Pd(II)-catalyzed synthesis of benzocyclobutenes I (R = 3-I, 2-F, 3,4-(F)2, etc.; R1 = H, Me, Bu; R2 = Me, Et) by methylene-selective C(sp3)-H arylation of ketones has been described. The reaction utilizes glycine as a transient directing group and a 2-pyridone ligand, which may govern the methylene selectivity by making intimate mol. associations with the substrate during concerted metalation-deprotonation. This reaction is shown to be highly selective for intramol. methylene C(sp3)-H arylation, thus enabling sequential C(sp3)-H functionalization.
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Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate