Shan, Xiang-Huan; Zheng, Hong-Xing; Yang, Bo; Tie, Lin; Fu, Jia-Le; Qu, Jian-Ping; Kang, Yan-Biao published the article 《Copper-catalyzed oxidative benzylic C-H cyclization via iminyl radical from intermolecular anion-radical redox relay》. Keywords: nitrile alkylaryl halide copper catalyst oxidative heterocyclization; indole preparation.They researched the compound: 1-(Bromomethyl)-2-iodobenzene( cas:40400-13-3 ).Computed Properties of C7H6BrI. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:40400-13-3) here.
The combination of base-promoted benzylic C-H cleavage and copper-catalyzed carbanion-radical redox relay was reported. Catalytic amount of naturally abundant and inexpensive copper salt, such as copper(II) sulfate, was used for anion-radical redox relay without any external oxidant. By avoiding using N-O/N-N homolysis or radical initiators to generate iminyl radicals, this strategy realized modular synthesis of N-H indoles and analogs from abundant feedstocks, such as toluene and nitrile derivatives, and also enabled rapid synthesis of large scale pharmaceuticals.
Here is just a brief introduction to this compound(40400-13-3)Computed Properties of C7H6BrI, more information about the compound(1-(Bromomethyl)-2-iodobenzene) is in the article, you can click the link below.
Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate