So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Jin, Ming; Yin, Shi-fu; Yang, Shang-Dong researched the compound: 1-(Bromomethyl)-2-iodobenzene( cas:40400-13-3 ).SDS of cas: 40400-13-3.They published the article 《Bismuth(III)-Catalyzed Sequential Enamine-Imine Tautomerism/2-Aza-Cope Rearrangement of Stable β-Enaminophosphonates: One-Pot Synthesis of β-Aminophosphonates》 about this compound( cas:40400-13-3 ) in Organic Letters. Keywords: beta aminophosphonate preparation tandem condensation Cope rearrangement phosphonoaldehyde amine; tandem condensation aza Cope rearrangement phosphonoaldehyde homoallylamine preparation aminophosphonate; bismuth triflate catalyst tandem condensation aza Cope rearrangement phosphonoaldehyde. We’ll tell you more about this compound (cas:40400-13-3).
Bismuth triflate-catalyzed condensation of phosphonoaldehydes OHCCHR1P(O)(OR2)2 with homoallylic amine H2NCPh2CH2CH:CH2 gives β-aminophosphonates I (3a-o; R1 = substituted benzyl, H, allyl, cinnamyl, iBu, cyclopropyl; R2 = Et iPr) via tandem aza-Cope rearrangement. A novel catalytic tautomeric transformation of a β-enaminophosphoryl and 2-aza-Cope rearrangement sequence has been successfully applied to the one-pot synthesis of β-aminophosphonates with high efficiency and good tolerance. In this tandem reaction, Bi(OTf)3 exhibits unique activities and promotes both of enamine-imine tautomerism and 2-aza-Cope rearrangement.
In some applications, this compound(40400-13-3)SDS of cas: 40400-13-3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate