COA of Formula: C7H14O6. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: (2R,3R,4S,5R,6R)-2-(Hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol, is researched, Molecular C7H14O6, CAS is 1824-94-8, about Cytotoxicity assessment of Malva Sylvestris crude extract on melanoma and lymphoma cell lines. Author is Rayssan, Raghda; Shawkat, Muayad S..
This article focus on the anal. of M.sylvestris methanolic leaves extract by GC-MS and the evaluation of its cytotoxic effect on two types of human cancerous cell lines which are melanoma and lymphoma cell lines. GC-MS anal. showed 29 peaks, the prominent peak was 22.942 peak area (RT 27.01): trans-Phytol; Cyclohexanol,5-methyl-2-(1-methylethyl)-,[1S-(1.alpha.2.beta.5.beta.)]; Dihydrogeraniol; Menthol,trans-1,3,trans-1,4; (+)-Isomenthol . The extract showed cytotoxicity against both melanoma and lymphoma cell lines and the cytotoxic effect was increased with the increasing of extract concentration, the cytotoxicity of the extract at 200 μL was 68.65% and 76.53% for lymphoma and melanoma cell lines resp., for reference cell line the cytotoxicity of the extract was 7% at 200 μL. This implicit that M.sylvestris extract has min. side effect on normal cells thus may be considered safe and potential candidate as anticancer agent.
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Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate