Continuously updated synthesis method about 40400-13-3

As far as I know, this compound(40400-13-3)Recommanded Product: 40400-13-3 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called L-Proline N-oxide dihydrazides as an efficient ligand for cross-coupling reactions of aryl iodides and bromides with amines and phenols, published in 2021-01-22, which mentions a compound: 40400-13-3, Name is 1-(Bromomethyl)-2-iodobenzene, Molecular C7H6BrI, Recommanded Product: 40400-13-3.

A novel catalytic system based on L-proline N-oxide/CuI was developed and applied to the cross-coupling reactions of various N- and O- nucleophilic reagents with aryl iodides and bromides. This strategy featured in the employment of an L-proline derived dihydrazides N-oxide compound as the superior supporting ligand. By using this protocol, a variety of products, including N-arylimidazoles, N-arylpyrazoles, N-arylpyrroles, N-arylamines, and aryl ethers, were synthesized with up to 99% yield.

As far as I know, this compound(40400-13-3)Recommanded Product: 40400-13-3 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate