SDS of cas: 1824-94-8. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: (2R,3R,4S,5R,6R)-2-(Hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol, is researched, Molecular C7H14O6, CAS is 1824-94-8, about Evaluation of MIC, MBC, MFC and anticancer activities of acylated methyl β-D-galactopyranoside esters. Author is Misbah, M. H. Md; Ferdous, Jannatul; Bulbul, Z. H. Md; Chowdhury, Tasneem S.; Dey, Sujan; Hasan, Imtiaj; Kawsar, Sarkar M. A..
A bacterial resistance gained by microorganisms to classical antimicrobials is current challenges. Searching of antimicrobial agents with new structure and mode of action is an essential strategy of research. Therefore, some acylated derivatives of Me β-D-galactopyranoside were employed as test compounds for in vitro antimicrobial functionality test against five human pathogenic bacteria and two phytopathogenic fungi.For comparative studies, biol. activity of standard antibiotics, Azithromycin and Nystatin were also carried out against these microorganisms. The study revealed that the tested samples exhibited moderate to good antibacterial and antifungal activities. It was also observed that the test substances were more effective against fungal phytopathogens than those of the bacterial strains. Encouragingly, a good number of test compounds exhibited better antimicrobial activity than the standard antibiotics employed. Min. Inhibition Concentration (MIC) and MBC test of Me 2,3,4-tri-O-(3-chlorobenzoyl)-6-O-pivaloyl-β-D-galactopyranoside 12 was conducted good result against S. aureus and MIC, MBC were found to be 312.5 μg/disk and 625 μg/disk, resp. In addition, MFC was invented to be 1250 μg/disk against Candida albicans. In vitro MTT assays revealed that compound 8 was effective against Ehrlich′s ascites carcinoma (EAC) cells, resulting in 12.72% and 2.11% cell growth inhibition at concentrations of 200 and 6.25 μg/mL, resp. So the acylated derivatives of D-galactopyranoside (2-14) may be considered as a potential source for developing new and better antimicrobial agents against a number of pathogenic organisms.
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Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate