Synthetic Route of 13440-07-8. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 13440-07-8, Name is Di(naphthalen-1-yl)phosphine oxide. In a document type is Article, introducing its new discovery.
A highly efficient [1,2]-Brook rearrangement of silyl glyoxylates has been developed using DBU as the organobase-catalyst. This [1,2]-Brook rearrangement is applicable to a number of thiols and secondary phosphine oxides containing acidic protons. These nucleophiles afford the corresponding Brook products in high yields. Using this methodology, a formal synthesis of anti-HIV drug compound lamivudine was realized.
If you are interested in 13440-07-8, you can contact me at any time and look forward to more communication.Synthetic Route of 13440-07-8
Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate