The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.131274-22-1, Name is Tri-tert-butylphosphonium tetrafluoroborate, molecular formula is C12H28BF4P. In a Article，once mentioned of 131274-22-1, Recommanded Product: Tri-tert-butylphosphonium tetrafluoroborate
(Chemical Equation Presented) This study describes the mechanism and selectivity pattern of the Pd0-catalyzed C(sp3)-H activation of a prototypical substrate bearing two linear alkyl groups. Experimentally, the use of the Pd/P(t-Bu)3 catalytic system leads to a ca. 7:3 mixture of olefin and benzocyclobutene (BCB) products. The C-H activation step was computed to be favored for the secondary position alpha to the benzylic carbon over the primary position beta to the benzylic carbon by more than 4 kcal mol-1, in line with previous selectivity trends on analogous substrates. The five-membered palladacycle obtained through this activation step may then follow two different pathways, which were computationally characterized: (1) decoordination of the protonated base and reductive elimination to give the BCB product and (2) proton transfer to the aryl ligand and base-mediated beta-H elimination to give the olefin product. Experiments conducted with deuterated substrates were in accordance with this mechanism. The difference between the highest activation barriers in the two pathways was computed to be 1.2 kcal mol-1 in favor of BCB formation. However, the use of a kinetic model revealed the critical influence of the kinetics of dissociation of HCO3- formed after the C-H activation step in actually directing the reaction toward either of the two pathways.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: Tri-tert-butylphosphonium tetrafluoroborate, you can also check out more blogs about131274-22-1
Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate