A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 155613-52-8, Name is (R)-1,1-Binaphthyl-2,2-diyl phosphorochloridate, molecular formula is C20H12ClO2P. In a Article，once mentioned of 155613-52-8, Application In Synthesis of (R)-1,1-Binaphthyl-2,2-diyl phosphorochloridate
A method for determining enantiomeric excess by mass spectrometry was employed to screen a family of chiral phosphite P,N-ligands for activity in the rhodium-catalyzed asymmetric hydrosilylation of ketones. The identification of an effective set of ligands was followed by preliminary studies of the reaction scope and mechanism. Asymmetric induction of 84-88% ee for larger-scale reactions was observed, which is close to the level of the best alternative catalysts previously discovered. The screening method was shown to be applicable to a variety of substrates without the need for special optimization.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Application In Synthesis of (R)-1,1-Binaphthyl-2,2-diyl phosphorochloridate, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 155613-52-8, in my other articles.
Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate