Synthetic Route of 84127-04-8, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 84127-04-8, C14H15O2P. A document type is Patent, introducing its new discovery.
The present invention relates to a P chiral pincer compound (II) and a palladiumcoordination compound (I) thereof, and synthesis methods of the two compounds. According to the present invention, the palladium coordination compound (I) (wherein X represents -Cl, R represents hydrogen atom or C1-C4 alkyl, and the chiralities of the two P are simultaneously R configurations or S configurations) is synthesized through a coordination reaction of the compound (II) and a divalent palladium salt; the palladium coordination compound (I) (wherein X is selected from -Br, -I, -OAc, -OTf, -BF4 and -SbF6) is synthesized through an anion exchange reaction of the palladium coordination compound (I) with the X represented by -Cl; and the palladium coordination compound (I) of the present invention can be adopted as the chiral catalyst so as to be used in a variety of asymmetric reactions such as asymmetric Micheal addition, asymmetric Heck coupling reactions, asymmetric Suzuki-Miyaura coupling reactions, asymmetric allylation reactions and the like. The formulas (I) and (II) are defined in the instruction.
If you are hungry for even more, make sure to check my other article about 84127-04-8. Synthetic Route of 84127-04-8
Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate