13440-07-8, Name is Di(naphthalen-1-yl)phosphine oxide, molecular formula is C20H15OP, belongs to chiral-phosphine-ligands compound, is a common compound. In a patnet, once mentioned the new application about 13440-07-8, Product Details of 13440-07-8
Asymmetric Morita?Baylis?Hillman Reaction: Catalyst Development and Mechanistic Insights Based on Mass Spectrometric Back-Reaction Screening
An efficient protocol for the evaluation of catalysts for the asymmetric Morita?Baylis?Hillman (MBH) reaction was developed. By mass spectrometric back-reaction screening of quasi-enantiomeric MBH products, an efficient bifunctional phosphine catalyst was identified that outperforms literature-known catalysts in the MBH reaction of methyl acrylate with aldehydes. The close match between the selectivities measured for the forward and back reaction and kinetic measurements provided strong evidence that the aldol step and not the subsequent proton transfer is rate- and enantioselectivity-determining.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Product Details of 13440-07-8. In my other articles, you can also check out more blogs about 13440-07-8
Reference：
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate