Synthetic Route of 791-28-6, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 791-28-6, Name is Triphenylphosphine oxide, SMILES is O=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3, belongs to chiral-phosphine-ligands compound. In a article, author is Major, Mate M., introduce new discover of the category.
Backbone effects in the synthesis, coordination chemistry and catalytic properties of new chiral heterobidentate ligands with P,N and S,N donor sets
Novel alkane-diyl based heterobidentate P,N and S,N ligands with the general formula (RRNCH)-R-1-N-2(R-3)(CH2)(n)CH(R-4)Q (R-1 = Me or iPr; R-2 = H or Me; R-3, R-4 = H or Me; n = 0, 2; Q = PPh2 or SPh) have been prepared starting from cyclic sulfate esters or naturally occurring compounds with C-1 symmetry. The length of the ligands’ backbone and the reaction conditions applied strongly affected the stereochemical outcome of the synthesis when using cyclic sulfates as starting materials. Palladium(II)-complexes of the new ligands were characterized by 1D and 2D NMR spectroscopy in solution and in several cases by X-ray crystallography in the solid phase. The structural versatility of the ligands enabled the straightforward comparison of the stereoselectivity of their coordination as a function of their tether length, backbone substitution pattern, donor sets and relative carbon atom configuration in their backbone. The catalytic features of the novel compounds were investigated in asymmetric allylic alkylation reactions where the tether length proved to be a crucial factor in determining enantioselectivity. (C) 2020 The Authors. Published by Elsevier B.V.
Synthetic Route of 791-28-6, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 791-28-6 is helpful to your research.
Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate