Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Product Details of 1486-28-8, 1486-28-8, Name is Methyldiphenylphosphine, molecular formula is C13H13P, belongs to chiral-phosphine-ligands compound. In a document, author is Yoshida, Masanori, introduce the new discover.
Asymmetric alpha-Allylation of alpha-Substituted beta-Ketoesters with Allyl Alcohols
Enantioselective alpha-allylation of alpha-substituted beta-ketoesters with simple allyl alcohols was successfully performed by synergistic catalysis with the catalyst combination of a chiral primary amino acid and an achiral palladium complex without additional promotors like acids or bases. The allylation reaction and generation of a chiral quaternary carbon stereocenter proceeded smoothly to produce alpha,alpha-disubstituted beta-ketoesters in high yields (91-99%) with high enantioselectivities (90-99% ee).
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1486-28-8. Product Details of 1486-28-8.
Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate