In an article, author is Wang, De, once mentioned the application of 18437-78-0, Quality Control of Tris(4-fluorophenyl)phosphine, Name is Tris(4-fluorophenyl)phosphine, molecular formula is C18H12F3P, molecular weight is 316.26, MDL number is MFCD00013553, category is chiral-phosphine-ligands. Now introduce a scientific discovery about this category.
Highly Regio- and Enantioselective Dienylation of p-Quinone Methides Enabled by an Organocatalyzed Isomerization/Addition Cascade of Allenoates
A novel catalytic asymmetric dienylation of para-quinone methides with allenoates has been developed. Under mild conditions catalyzed by (R)-SITCP, various dienylated bisarylmethides were obtained in moderate to good yields (up to 82% yield) and excellent enantioselectivities (90-98% ees). The efficacy and robustness were demonstrated by 27 examples of chiral dienylation products. A plausible mechanism, which involved 1,2 H-shift and umpolung of allenoates, was proposed based on deuterium labeling experiments and previous reports.
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Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate