Reference of 1486-28-8, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 1486-28-8, Name is Methyldiphenylphosphine, SMILES is CP(C1=CC=CC=C1)C2=CC=CC=C2, belongs to chiral-phosphine-ligands compound. In a article, author is Du, Hong-Quan, introduce new discover of the category.
Rh-Catalyzed Asymmetric Hydrogenation of (Z)-beta-Phosphorylated Enamides: Highly Enantioselective Access to beta-Arninophosphines
A catalytic asymmetric hydrogenation of beta-phosphorylated enamides for enantioselective access to optically active beta-aminophosphine derivatives is reported. Critical to the success of this method was the employment of rhodium catalysis in concert with an unsymmetrical hybrid chiral phosphine-phosphoramidite ligand. A wide range of aromatic beta-phosphorylated enamides could be hydrogenated in full conversion and with perfect enantioselectivity even at low catalyst loadings (S/C = 1000). beta-Aminophosphine oxides could be readily hydrolyzed and reduced, thus providing an efficient route to catalytically important chiral beta-aminophosphines.
Reference of 1486-28-8, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 1486-28-8 is helpful to your research.
Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate