Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Recommanded Product: Benzyldiphenylphosphine7650-91-1, Name is Benzyldiphenylphosphine, SMILES is P(C1=CC=CC=C1)(CC2=CC=CC=C2)C3=CC=CC=C3, belongs to chiral-phosphine-ligands compound. In a article, author is Ravutsov, Martin, introduce new discover of the category.
Directed ortho-lithiation as a tool for synthesis of chiral 1,2-disubstituted arylsulfonamides
The directed ortho-lithiation is demonstrated as an excellent method for additional functionalization of chiral phenyl and naphthyl sulfonamides. The chirality was introduced through sulfonamide formation with a series of chiral amines prior to the lithiation process. In the case of naphthyl sulfonamides the regioselectivity of the directed ortho-lithiation was studied and optimized. The approach was shown to provide facile ortho-functionalization and was applied for the synthesis of chiral 1,2-sulfonamido phosphine derivatives. The latter were evaluated as P,O-ligands in Pd-catalyzed asymmetric allylic substitution. [GRAPHICS]
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 7650-91-1. Recommanded Product: Benzyldiphenylphosphine.
Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate