Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 6224-63-1, Name is Tri-m-tolylphosphine, molecular formula is C21H21P. In an article, author is Chu, Haoke,once mentioned of 6224-63-1, COA of Formula: C21H21P.
Asymmetric Dearomatization of Indole by Palladium/PC-Phos-Catalyzed Dynamic Kinetic Transformation
A palladium-catalyzed intermolecular dynamic kinetic asymmetric dearomatization of 3-arylindoles with internal alkynes was developed with the use of achiral Xantphos and chiral sulfinamide phosphine ligand (PC-Phos) as the co-ligands. This method could deliver various spiro[indene-1,3 ‘-indole] compounds in good yields (up to 95 % yield) with up to 98 % ee. The salient features of the transformation include the use of readily available substrates, ease of scale-up and the versatile functionalization of the products. The mechanistic experiments gave some insights on active intermediates.
Interested yet? Keep reading other articles of 6224-63-1, you can contact me at any time and look forward to more communication. COA of Formula: C21H21P.
Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate