Synthetic Route of 1486-28-8, Redox catalysis has been broadly utilized in electrochemical synthesis due to its kinetic advantages over direct electrolysis. The appropriate choice of redox mediator can avoid electrode passivation and overpotential. 1486-28-8, Name is Methyldiphenylphosphine, SMILES is CP(C1=CC=CC=C1)C2=CC=CC=C2, belongs to chiral-phosphine-ligands compound. In a article, author is Nemethova, Ivana, introduce new discover of the category.
Reductive alkylation of imines via asymmetric Cu-catalyzed addition of organozirconium reagents
Chiral amines are important as medicines or agrochemicals. They are often assembled by nucleophilic addition to corresponding compounds featuring C=N bond. Pre-made organometallics are typical nucleophiles in this reaction. In this work, we describe asymmetric reductive alkylation of imines with alkenes. Hydrozirconation of these alkenes generated organozirconium species in situ. The transformation is catalyzed by Cu-Segphos complex and affords chiral amines in enantioselectivities up to 93% ee. (C) 2020 Elsevier B.V. All rights reserved.
Synthetic Route of 1486-28-8, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 1486-28-8 is helpful to your research.
Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate