Application of 1486-28-8, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 1486-28-8, Name is Methyldiphenylphosphine, SMILES is CP(C1=CC=CC=C1)C2=CC=CC=C2, belongs to chiral-phosphine-ligands compound. In a article, author is Magne, Valentin, introduce new discover of the category.
Chiral Phosphathiahelicenes: Improved Synthetic Approach and Uses in Enantioselective Gold(I)-Catalyzed [2+2] Cycloadditions of N-Homoallenyl Tryptamines
A chiral phosphathiahelicene scaffold displaying a CI phosphole and a thiophene unit as the terminal rings of the helical sequence has been synthesized and characterized by spectroscopic methods and X-ray diffraction studies. The phosphine oxides (HelPhos-V oxides) have been obtained following a robust and scalable synthetic approach, based on a nickel-promoted alkyne cyclotrimerization reaction. Then, late-stage functionalization has been carried out via a bromination/palladium coupling reaction sequence. The HelPhos-V gold(I) complexes have been used as catalysts in the unprecedented enantioselective [2 + 2] cyclization of N-homoallenyl tryptamine derivatives, to afford indolenine-fused cyclobutanes in good isolated yields, with enantiomeric excesses up to 93%.
Application of 1486-28-8, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 1486-28-8 is helpful to your research.
Reference:
Phosphine ligand,
,Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate