Synthetic Route of 17261-28-8, An article , which mentions 17261-28-8, molecular formula is C19H15O2P. The compound – 2-(Diphenylphosphino)benzoic acid played an important role in people’s production and life.
Synthesis of novel bidentate P-chiral diaminophosphine oxide preligands: Application to Pd-catalyzed asymmetric allylic substitution reactions
We developed a novel (S)-L-phenylalanine derived-bidentate chiral diaminophosphine oxide (DIAPHOX) preligand (S,SP)-9b, which was successfully applied to Pd-catalyzed asymmetric allylic alkylation and amination. Using the Pd-(S,SP)-9b catalyst system, asymmetric allylic alkylation and amination proceeded very smoothly, affording the corresponding products in excellent yield with high enantiomeric excess. It is noteworthy that both enantiomers were accessible with high enantiomeric purity using the structurally related DIAPHOX preligands (S,SP)-9b and a monodentate chiral diaminophosphine oxide preligand (S,RP)-10a, both of which can be prepared from a single chiral source, (S)-L-phenylalanine.
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Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate