224311-49-3, Name is 2′-(Di-tert-butylphosphino)-N,N-dimethyl-[1,1′-biphenyl]-2-amine, molecular formula is C22H32NP, belongs to chiral-phosphine-ligands compound, is a common compound. In a patnet, once mentioned the new application about 224311-49-3, Computed Properties of C22H32NP
Novel electron-rich bulky phosphine ligands facilitate the palladium-catalyzed preparation of diaryl ethers
A general method for the palladium-catalyzed formation of diaryl ethers is described. Electron-rich, bulky aryldialkylphosphine ligands, in which the two alkyl groups are either tert-butyl or 1-adamantyl, are the key to the success of the transformation. A wide range of electron-deficient, electronically neutral and electron-rich aryl bromides, chlorides, and triflates can be combined with a variety of phenols with the use of sodium hydride or potassium phosphate as base in toluene at 100 C. The bulky yet basic nature of the phosphine ligand is thought to be responsible for increasing the rate of reductive elimination of the diaryl ether from palladium.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Computed Properties of C22H32NP. In my other articles, you can also check out more blogs about 224311-49-3
Reference£º
Phosphine ligand,
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate