With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.
General procedure: Complex 1b was prepared by a ligand substitution reaction. A mixture of triphenylphosphine (51.8 mg, 0.197 mmol) and [Pt{N(COPh)CH2COO}(cod)] 1a (46.5 mg, 0.097 mmol) was dissolved in dichloromethane (4 mL) and left to stand for 5 min., then filtered through a cotton-plugged glass Pasteur pipette and washed through with a further 0.5 mL dichloromethane. Petroleum spirits (25 mL) was added, giving white needle crystals on standing overnight. Upon subsequent evaporation of around one third of the solvent, further product formed which, following removal of the supernatant, was washed with petroleum spirits (ca. 2 mL) and dried under vacuum for 3 h to give 95.7 mg (97percent) of 1b¡¤1.5CH2Cl2.
12150-46-8, 12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Article; Sim, Sophie A.; Saunders, Graham C.; Lane, Joseph R.; Henderson, William; Inorganica Chimica Acta; vol. 450; (2016); p. 285 – 292;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate