18437-78-0, Tris(4-fluorophenyl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: 4.3.31 methyl 2-phenyl-5-(4-fluorophenyl)oxazole-4-carboxylate (4k) A suspension of Pd(OAc)2 (10 mol percent), Ar3P (0.33 mmol or 0.75 mmol), AgOAc (3.0 mmol), TFA (1.0 mmol) and azole-4-carboxylates (0.5 mmol) in NMP (2 mL) was introduced to a Schlenk tube. After stirring at 120 C under argon for 24 h (reactions with 0.33 mmol of Ph3P), or 48 h (reactions with 0.75 mmol of Ph3P), the reaction mixture was diluted with ethyl acetate, and then filtered through a pad of Celite. Volatiles were removed in vacuo to give the crude products, which was purified by flash column chromatography on silica gel to afford pure arylated products Yield 89 mg (60percent). White solid, mp 140-142 ¡ãC; 1H NMR (300 MHz, CDCl3) delta 3.95 (s, 3H), 7.16 (t, J=8.7 Hz, 2H), 7.44-7.47 (m, 3H), 7.09-7.18 (m, 4H) ppm; 13C NMR (75 MHz, CDCl3) delta 164.4, 161.6, 161.0, 158.6, 153.3, 130.1, 129.6, 129.5, 127.8, 126.6, 125.7, 125.1, 122.2, 122.1, 114.7, 114.4, 51.3 ppm; IR (KBr) 2950, 2844, 1715, 1505, 1434, 1355, 1235, 1094, 1009, 844, 708 cm-1; HRMS (ESI) calcd for [C17H12FNO3+H]+ 298.0874, found 298.0876.
18437-78-0, As the paragraph descriping shows that 18437-78-0 is playing an increasingly important role.
Reference£º
Article; Li, Ziyuan; Zhou, Haipin; Xu, Jinyi; Wu, Xiaoming; Yao, Hequan; Tetrahedron; vol. 69; 15; (2013); p. 3281 – 3286;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate