With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4020-99-9,Methoxydiphenylphosphine,as a common compound, the synthetic route is as follows.
In 1000 ml by adding reaction bottle 99.5g (0.46mol) diphenyl methoxy phosphorus (? 99.5% purity) and 72g m-methoxybenzyl chloride (0.42mol) (content ? 99.2%) making between, under stirring condition temperature to 55 C, and at this temperature thermal insulation 10 hours, and cooled to the end of the 10 C, directly enters the reaction of the next., 4020-99-9
4020-99-9 Methoxydiphenylphosphine 77636, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Patent; Suzhou Chenghe Pharmaceutical & Chemical Co., Ltd.; Xia, qiujing; (5 pag.)CN105503954; (2016); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate