Simple exploration of 1070663-78-3

As the paragraph descriping shows that 1070663-78-3 is playing an increasingly important role.

1070663-78-3, Dicyclohexyl(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

1070663-78-3, EXAMPLE TWELVE: Synthesis of Precatalyst 10; Ligand 1 (BrettPhos)An oven-dried schlenk tube, which was equipped with a magnetic stir bar and fitted with a rubber septum, was charged with Me2Pd(TMEDA) (253 mg, 1 mmol) and 1 (537 mg, 1 mmol). The vessel was evacuated and backfilled with argon (this process was repeated a total of 3 times) and the 2-(2-chorophenyl)ethylamine (156 mg, 1 mmol) and MTBE (8 mL) were added via syringe and the reaction mixture was heated to 55 0C for 5 h. The reaction mixture was then cooled to 0 0C and a white precipate was filtered and washed with cold MTBE. The white product was then taken up in CH2Cl2 and concentrated under reduced pressure (done to remove any remaining MTBE) to yield the product as a white solid (645 mg, 93% yield). 1H NMR (300 MHz, CDCl3) delta: 7.17 (s, 2H), 7.09-6.84 (m, 6H), 3.85 (s, 3H), 3.38 (s, 3H), 3.17-0.00 (m, 49 H) ppm. 31P NMR (121 MHz, CDCl3) delta: 42.2 ppm. IR (neat, cm”1): 3303, 2929, 1658, 1462, 1384, 1256, 1010, 755.

As the paragraph descriping shows that 1070663-78-3 is playing an increasingly important role.

Reference£º
Patent; MASSACHUSETTS INSTITUTE OF TECHNOLOGY; WO2009/76622; (2009); A2;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate