With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.607-01-2,Ethyldiphenylphosphine,as a common compound, the synthetic route is as follows.
Accurately weighed ethyl diphenylphosphine (123 muL, 0.6 mmol),1,10-Phenanthroline (0.4698 g, 2.4 mmol) was added to a 25 mL Schlenk reaction flask.Then 3,5-dimethyl iodobenzene (144 muL, 0.9 mmol) was added and the solvent was dichloromethane (2 mL).The reaction was carried out at 75 C for 30 h. After the reaction,Extract with ethyl acetate/water and dry the organic phase with anhydrous sodium sulfate.The solvent was removed under reduced pressure.Separation of silica gel column using petroleum ether/ethyl acetate as eluentThe yield of the product was 40%., 607-01-2
The synthetic route of 607-01-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Dalian University of Technology; Yu Xiaoqiang; Bao Ming; Feng Xiujuan; Yin Qing; (15 pag.)CN109970789; (2019); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate