With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.18437-78-0,Tris(4-fluorophenyl)phosphine,as a common compound, the synthetic route is as follows.
General procedure: Complex 1 was synthesized by the simultaneous and dropwise addition of tris-(4-fluorophenyl)phosphine(0.316 g, 1 mmol) in acetone and sodium 4-benzylpiperazine-1-carbodithioate (0.274 g, 1 mmol)in methanol to a methanolic suspension of palladium(II) chloride (0.177 g, 1 mmol). The reaction mixturewas refluxed for 5 h with constant stirring. The resulting orange-colored solution was filtered androtary evaporated to obtained orange solid (scheme 1). It was dried and re-dissolved in chloroform,and on slow evaporation needle-like crystals were obtained. Complexes 2 and 3 were synthesized bythe same method (scheme 1).
18437-78-0, The synthetic route of 18437-78-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Khan, Shahan Zeb; Amir, Muhammad Kashif; Abbasi, Rashda; Tahir, Muhammad Nawaz; Zia-ur-Rehman; Journal of Coordination Chemistry; vol. 69; 20; (2016); p. 2999 – 3009;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate