With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13440-07-8,Di(naphthalen-1-yl)phosphine oxide,as a common compound, the synthetic route is as follows.
0.5 mmol of naphthyl diphenylphosphine oxide, 0.25 mmol of potassium carbonate and 0.75 mmol of methyl thiophenol were weighed into 10 mLThe flask was stirred at room temperature for 6 hours. After the reaction, the tetrahydrofuran solvent was removed using a rotary evaporator and the residue was dissolved in lmL of methylene chloride. The residue was purified by silica gel column chromatography to obtain Color transparent liquid, the yield was 87%., 13440-07-8
13440-07-8 Di(naphthalen-1-yl)phosphine oxide 23110917, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Patent; Guangdong University of Technology; Yan Xinxing; Chen Qian; Wen Chunxiao; Zeng Jiekun; Huang Yulin; Wang Xiaofeng; Chen Ziming; Huo Yanping; Du Zhiyun; Zhang Kun; (29 pag.)CN106928272; (2017); A;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate