With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.50777-76-9,2-(Diphenylphosphino)benzaldehyde,as a common compound, the synthetic route is as follows.
50777-76-9, The synthesis of the iminophosphine ligand carryingalkoxylsilane moiety A was performed through the reactive distillation of 2-(diphenylphosphino)benzaldehyde(0.500 g) with 3-(aminopropyl)trimethoxysilane (0.250 g)in dry toluene (25 mL). After 5 h, we obtained a yellowoily liquid by careful removal of toluene under vacuum(85 percent yield).1H NMR (400 MHz, CD2Cl2): d = 8.8 (s, 1H), 8.02 (s,1H), 7.45?7.27 (m, 12 H), 6.91 (s, 1 H), 3.53 (s, 9 H), 3.46(m, 2 H), 1.68?1.60 (m, 2 H), 0.58?0.52 (m, 2 H); 13CNMR (100 MHz, CD2Cl2): d = 158.57, 134.14, 128.79,65.13, 50.82, 24.62, 8.73 ppm; 31P NMR: (300 MHz,CD2Cl2, ppm) d = -13.07 ppm.
As the paragraph descriping shows that 50777-76-9 is playing an increasingly important role.
Reference£º
Article; Upadhyay, Praveenkumar Ramprakash; Srivastava, Vivek; Catalysis Letters; vol. 146; 8; (2016); p. 1478 – 1486;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate