17261-28-8, 2-(Diphenylphosphino)benzoic acid is a chiral-phosphine-ligands compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
N,N’-Dicyclohexylcarbodiimide (163 mg, 0.79 mmol) and 4-dimethylaminopyridine (5 mg, 0.039 mmol) were added to a solution of 2-(diphenylphosphino)benzoic acid (220.0 mg, 0.72 mmol) in anhydrous CH2Cl2 (30 mL) under argon with stirring at room temperature. After 30 min, fluorescein monomethyl ether (249 mg, 0.72 mmol) was added and the resulting mixture was stirred at room temperature overnight. The reaction mixture was concentrated under vacuum and cold acetone was added to dissolve the crude product. The insoluble urea by-product was removed by filtration. The filtrate was concentrated and the residue was purified by silica gel column chromatography (EtOAc /pet.ether=1:2) to provide 1 as a pale yellow solid (280 mg, 61percent)., 17261-28-8
17261-28-8 2-(Diphenylphosphino)benzoic acid 87021, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Article; Miao, Zhengrui; Reisz, Julie A.; Mitroka, Susan M.; Pan, Jia; Xian, Ming; King, S. Bruce; Bioorganic and Medicinal Chemistry Letters; vol. 25; 1; (2015); p. 16 – 19;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate