With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.
To a dichloromethane solution (20cm3) of [PtCl2(PhCN)2] (100 mg, 0.21 mmol), a solution of dppf (118 mg, 0.21 mmol) in dichloromethane was added. The resulting mixture was kept on stirring for 4 hours at room temperature. Solvent was evaporated under reduced pressure and residue was washed thoroughly with hexane followed by diethyl ether to remove excess phosphine. The residue was extracted with dichloromethane, filtered and passed through a Florisil Column. The ensuing solution at room temperature resulted yellow crystals (yield 152 mg, 87percent). Anal. Calcd. for C34H28P2FePtCl2: C, 49.78; H, 3.44percent. Found: C, 49.76; H, 3.46percent. 1H NMR (CDCl3) delta: 4.19 (br, 4H, C5H4), 4.37 (br, 4H, C5H4), 7.37?7.47 (m, Ph), 7.86 (br, Ph), 7.67-7.61 (m, Ph); 31P{1H}NMR (CDCl3) delta?:13.1 [1J(Pt-P) = 3776 Hz] ppm.
12150-46-8, As the paragraph descriping shows that 12150-46-8 is playing an increasingly important role.
Reference£º
Article; Chauhan, Rohit Singh; Cordes, David B.; Slawin, Alexandra M.Z.; Yadav, Seema; Dash, Chandrakanta; Inorganica Chimica Acta; vol. 478; (2018); p. 125 – 129;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate