With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.12150-46-8,1,1-Bis(diphenylphosphino)ferrocene,as a common compound, the synthetic route is as follows.
General procedure: Fe2(CO)6(mu-edt) (1) (100 mg, 0.268 mmol), Me3NO(21 mg, 0.280 mmol) and dppm (104 mg, 0.271 mmol) were heated in boiling acetonitrile (15 mL) for 30 min. After cooling to room temperature, the volatiles were removed under reduced pressure and the residue chromatographed by TLC on silica gel. Elution with hexane/CH2Cl2 (7:3, v/v) developed two bands. The faster-moving band afforded Fe2(CO)5(kappa1-dppm)(mu-edt) (3) (135 mg,69 percent) as red crystals, while the slower-moving band gave Fe2(CO)4(mu-dppm)(mu-edt) (4) [23] (17 mg, 9 percent) as red crystals after recrystallization from hexane/CH2Cl2 at 4 C., 12150-46-8
12150-46-8 1,1-Bis(diphenylphosphino)ferrocene 51341936, achiral-phosphine-ligands compound, is more and more widely used in various fields.
Reference£º
Article; Rana, Shahed; Ghosh, Shishir; Hossain, Md. Kamal; Rahaman, Ahibur; Hogarth, Graeme; Kabir, Shariff E.; Transition Metal Chemistry; vol. 41; 8; (2016); p. 933 – 942;,
Phosphine ligand
Chiral phosphine ligands in asymmetric synthesis. Molecular structure and absolute configuration of (1,5-cyclooctadiene)-(2S,3S)-2,3-bis(diphenylphosphino)butanerhodium(I) perchlorate tetrahydrofuran solvate